(My wife has a love-hate relationship with ibuprofen: it makes her drowsy, but it’s also the only thing that soothes her menstrual cramps.)

Wife: “Ooh… cramps just kicked in. Ibuprofen up the wazoo.”

Me: “That seems less than ideal. I don’t think your body will absorb it properly if you put it up your wazoo.”

Wife: “Oh, my God. You’re ridiculous.”